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ISRCTN
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ISRCTN16800815
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ClinicalTrials.gov identifier
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Public title
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Telephone-administered cognitive behaviour therapy (CBT) for the treatment of obsessive compulsive disorder: A randomized controlled trial
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Scientific title
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Acronym
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N/A
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Serial number at source
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RDO/28/1/26
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Study hypothesis
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Exposure therapy and response prevention will yield equivalent clinical outcomes whether delivered by telephone or by face to face therapist contact in the treatment of obsessive-compulsive disorder
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Lay summary
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised controlled trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Obsessive-compulsive disorder (OCD)
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Participants - inclusion criteria
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1. Obsessive-compulsive disorder as the main presenting problem
2. Meet Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria for OCD
3. Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score of 16 and over
4. Aged between 16-65
5. Agree to, and give written consent to participate in the study
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Participants - exclusion criteria
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1. Obsessions without overt compulsions
2. Obsessional slowness
3. Organic brain disease
4. On a stable dose of antidepressants or anxiolytic medication for less than 3 months
5. Past or present psychosis
6. Meet DSM-IV criteria for substance abuse or dependence
7. Currently on more than 10 mg of Diazepam or equivalent daily
8. Severe depression >30 on Beck Depression Inventory (BDI)
9. Suicidal intent
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Anticipated start date
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01/10/2000
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Anticipated end date
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30/09/2002
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Status of trial
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Completed |
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Patient information material
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Target number of participants
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80
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Interventions
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Exposure therapy and response prevention delivered by either telephone or face to face
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Primary outcome measure(s)
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CBT delivered by telephone shows equivalent clinical outcome as face to face therapy and similar levels of satisfaction were reported.
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Secondary outcome measure(s)
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Cost-minimisation analysis shows that treatment by telephone is cheaper than face to face CBT. The main cost-driver is treatment time defined by the protocol and, for telephone-administered CBT, this duration was shorter.
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Sources of funding
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North West Research and Development Support Unit, Salford (Ref: RDO/28/1/26) - regional NHS R&D funding stream
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Trial website
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Publications
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Results in:
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=16935946
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Contact name
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Prof
Karina
Lovell
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Address
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School of Nursing
Midwifery & Social Work
The University of Manchester
Oxford Road
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City/town
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Manchester
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Zip/Postcode
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M13 9PL
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Country
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United Kingdom
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Sponsor
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North West Research and Development Support Unit (UK)
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Address
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c/o Ms Sue Riley
Institute for Public Health Research & Policy
The University of Salford
4th Floor Humphrey Booth House
Hulme Place
The Crescent
Salford
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City/town
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Manchester
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Zip/Postcode
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M5 4AO
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Country
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United Kingdom
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Date applied
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25/08/2005
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Last edited
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13/08/2007
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Date ISRCTN assigned
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13/09/2005
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