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ISRCTN
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ISRCTN11165766
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ClinicalTrials.gov identifier
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Public title
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The influence of low dose aspirin therapy on perioperative primary haemostasis in patients with vascular disease undergoing orthopaedic surgery
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Scientific title
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Acronym
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N/A
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Serial number at source
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N0557093705
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Study hypothesis
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How long does it take for the bleeding time to return to normal after stopping aspirin?
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised double blind placebo controlled trial.
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Haemostasis
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Participants - inclusion criteria
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100 Patients undergoing orthopaedic surgery.
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Participants - exclusion criteria
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Does not meet inclusion criteria
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Anticipated start date
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01/10/2000
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Anticipated end date
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31/10/2004
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Status of trial
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Completed |
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Patient information material
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Target number of participants
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100
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Interventions
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Each patient receives three containers of tablets (5+3+2) containing either aspirin or placebo. Random allocation to:
1. 10 days aspirin
2. 8 days aspirin + 2 days placebo
3. 5 days aspirin + 5 days placebo
4. 10 days placebo
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Primary outcome measure(s)
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Bleeding times on day of recruitment, morning of surgery and after surgery.
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Secondary outcome measure(s)
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Not provided at time of registration
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Sources of funding
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The Dudley Group of Hospitals NHS Trust (UK)
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Trial website
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Publications
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Contact name
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Dr
Julian
Sonksen
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Address
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Department of Anaesthetics
Russells Hall Hospital
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City/town
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Dudley
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Zip/Postcode
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DY1 2HQ
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Country
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United Kingdom
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Sponsor
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Record provided by the NHS Trusts Clinical Trials Register - Department of Health (UK)
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Address
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The Department of Health
Richmond House
79 Whitehall
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City/town
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London
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Zip/Postcode
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SW1A 2NL
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Country
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United Kingdom
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Tel
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+44 (0)20 7307 2622
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Fax
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+44 (0)20 7307 2623
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Email
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dhmail@doh.gsi.org.uk
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Sponsor website:
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http://www.doh.gov.uk
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Date applied
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12/09/2003
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Last edited
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10/07/2009
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Date ISRCTN assigned
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12/09/2003
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