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ISRCTN
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ISRCTN09811591
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ClinicalTrials.gov identifier
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Public title
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Cluster randomised controlled trial of an educational intervention to optimise antibiotic prescribing for acute cough
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Scientific title
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Acronym
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N/A
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Serial number at source
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N/A
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Study hypothesis
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This study aims to establish a valid estimate of the effect of perceived patient demand on General Practitioners (GPs) antibiotic prescribing, specifically for patients consulting with acute cough as one of the most prominent complaints, and to contribute to the necessary understanding of this complex prescription decision.
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Ethics approval
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This study was approved by the medical ethics committee of the University of Antwerp (A99-088).
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Study design
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Randomised controlled trial
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Countries of recruitment
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Belgium
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Disease/condition/study domain
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Acute cough
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Participants - inclusion criteria
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Flemish GPs randomised participants into an intervention and a control group including:
1. Immunocompetent patients
2. Aged 18 - 65 years old
3. With a new or worsening cough present for less than 30 days as (one of the) most prominent complaint(s) and as the reason for a first encounter at the GPs practice
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Participants - exclusion criteria
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Not provided at time of registration
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Anticipated start date
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01/01/2000
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Anticipated end date
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01/01/2002
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Status of trial
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Completed
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Patient information material
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Target number of participants
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85 Flemish GPs
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Interventions
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Only the GPs in the intervention group received our guideline for the management of acute cough, followed by an educational outreach visit to discuss the implementation of the guideline and a postal reminder with the key message of the guideline.
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Primary outcome measure(s)
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The antibiotic prescribing rate by GPs for adult patients with acute cough.
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Secondary outcome measure(s)
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1. Type of antibiotics prescribed, if any
2. Change in antibiotic prescribing affecting symptom resolution
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Sources of funding
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1. Fund for Scientific Research, Flanders (Belgium) - Samuel Coenen was research assistant
2. The Scientific Society of Flemish General Practitioners (Belgium) - funded the development of the guideline for the management of acute cough
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Trial website
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Publications
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Results in http://www.ncbi.nlm.nih.gov/sites/entrez?db=PubMed&cmd=Retrieve&list_uids=16536958
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Contact name
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Mr
Samuel
Coenen
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Address
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Centre for General Practice
University of Antwerp
Universiteitsplein 1
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City/town
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Antwerp
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Zip/Postcode
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B-2610
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Country
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Belgium
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Tel
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+32 (0)3 820 25 25
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Fax
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+32 (0)3 820 25 26
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Email
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samuel.coenen@ua.ac.be
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Sponsor
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University of Antwerp (Belgium)
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Address
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Centre for General Practice
Universiteitsplein 1
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City/town
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Antwerp
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Zip/Postcode
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B-2610
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Country
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Belgium
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Sponsor website:
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http://www.ua.ac.be/
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Date applied
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15/10/2002
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Last edited
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09/10/2007
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Date ISRCTN assigned
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15/10/2002
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