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ISRCTN
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ISRCTN08067387
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ClinicalTrials.gov identifier
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Public title
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A more intensive approach to diagnosis and management of asthma in primary care: a randomised controlled trial
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Scientific title
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Acronym
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N/A
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Serial number at source
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03/050
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Study hypothesis
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Use of exhaled nitric oxide will result in fewer asthma exacerbations.
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Lay summary
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Ethics approval
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University Hospitals of Leicester (ref. no.: 9141) and the Leicester Primary Research Care Alliance (ref. no.: 0274).
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Study design
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Randomised controlled trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Asthma
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Participants - inclusion criteria
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1. Asthma
2. On treatment, providing it is a repeat prescription i.e., the patient suffers from chronic asthma
3. Aged 18-85
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Participants - exclusion criteria
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Recent exacerbation
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Anticipated start date
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01/01/2004
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Anticipated end date
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01/01/2006
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Status of trial
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Completed |
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Patient information material
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Target number of participants
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200
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Interventions
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Titrate steroid dose on basis of exhaled nitric oxide versus control group receiving treatment as per current BTS (British Thoracic Society) guidelines.
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Primary outcome measure(s)
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Asthma exacerbations.
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Secondary outcome measure(s)
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Steroid dose (area under curve).
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Sources of funding
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Asthma UK
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Trial website
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Publications
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Results in:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=retrieve&db=pubmed&list_uids=17496226
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Contact name
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Dr
Dominick
Shaw
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Address
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17 Arleston Drive
Wollaton
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City/town
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Nottingham
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Zip/Postcode
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NG8 2FR
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Country
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United Kingdom
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Sponsor
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Asthma UK (UK)
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Address
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Summit House
70 Wilson Street
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City/town
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London
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Zip/Postcode
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EC2A 2DB
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Country
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United Kingdom
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Sponsor website:
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http://www.asthma.org.uk/
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Date applied
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13/07/2006
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Last edited
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10/03/2008
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Date ISRCTN assigned
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17/08/2006
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