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ISRCTN
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ISRCTN05615277
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ClinicalTrials.gov identifier
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Public title
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Training of cognitive functions in aging population - effectiveness and use
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Scientific title
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Training of cognitive functions in aging population - an interventional single centre controlled trial of effectiveness and use of a memory training program
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Acronym
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NPV2TP
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Serial number at source
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2D06013
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Study hypothesis
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1. To test the effect of a publicly available memory training program on cognitive functions and self-evaluation of the participants, measured by subjective and objective psychological methods
2. To test the effect of this memory training on relevant opinions of the participants' significant others
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Ethics approval
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The Ethical Committee of Prague Psychiatric Center and Psychiatric Hospital Bohnice approved on the 13th December 2006 (ref: 230/06)
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Study design
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Interventional single centre non-randomised controlled trial
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Countries of recruitment
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Czech Republic
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Disease/condition/study domain
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Cognitive status
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Participants - inclusion criteria
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1. Community-dwelling senior citizens, aged above 50 years, either sex
2. Cognitively healthy volunteers: Mini-Mental State Examination (MMSE) greater than 26
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Participants - exclusion criteria
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Impaired cognitive or functional status
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Anticipated start date
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02/04/2007
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Anticipated end date
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31/12/2008
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Status of trial
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Completed |
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Patient information material
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Not available in web format, please use the contact details below to request a patient information sheet
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Target number of participants
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Experimental group: 170; Control group: 90; Total: 260
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Interventions
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The intervention is a lectured memory training program in twenty 45-minute lessons in 9 block in 5 weeks in a large-group setting. It is a program that is available nationwide in the Czech Republic through a network of memory trainers, members of the Czech Society for Memory Training and Brain Jogging. Each session included:
1. Mnemonics theory and practice (mnemonic techniques: categorisation, visualisation, acrostics, acronyms, loci method, chunking, peg word system, names and faces linking method)
2. Theoretical information on brain functioning, ageing and neuroscientific findings (memory processes, hemispheric specialisation, etc.)
3. Various cognitive exercises (visuospatial skills, attention, semantic associations, anagrams, etc.)
4. Healthy ageing tips (e.g. nutrition, mental effort, social activity, physical exercise, etc.)
5. Demanding homework assessment
Both groups had the same schedule of assessments:
Assessment 1: baseline
Assessment 2: 6 - 8 weeks later
Assessment 3: 6 months later
The experimental group started in April 2007 and finished in November 2007. The control group started in December 2007 and finished in July 2008. The intervention followed Assessment 1, for the experimental group only.
Scientific contact details:
Dr Hana Stepankova
Prague Psychiatric Center
Ustavni 91
18103 Prague 8
Czech Republic
Email: stepankova@pcp.lf3.cuni.cz
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Primary outcome measure(s)
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Measured at assessments 2 and 3:
1. Objective cognitive outcomes, measured using Auditory-Verbal Learning Test, Subtest Logical Memory of Wechsler Memory Scale III, Trail Making Test, Telephone Numbers Test, Shopping List Test
2. Subjective self-evaluation outcomes, measured using Subjective Cognitive Scale, Cognitive Failures Questionnaire and SOS-10
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Secondary outcome measure(s)
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Subjective self-evaluation outcomes, measured using structured interviews, measured at assessments 2 and 3.
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Sources of funding
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Ministry of Education, Youth and Sports (Czech Republic) (ref: MSMT 2D06013)
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Trial website
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http://www.pcp.lf3.cuni.cz/pcpout/vyzkumne_projekty.htm
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Publications
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Contact name
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Dr
Marek
Preiss
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Address
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Prague Psychiatric Center
Ustavni 91
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City/town
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Prague 8
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Zip/Postcode
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18103
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Country
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Czech Republic
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Sponsor
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Ministry of Education, Youth and Sports (Czech Republic)
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Address
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Karmelitska 7
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City/town
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Prague 1
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Zip/Postcode
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11812
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Country
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Czech Republic
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Tel
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+420 234 811 111
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Fax
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+420 234 811 753
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Email
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info@msmt.cz
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Sponsor website:
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http://www.msmt.cz/
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Date applied
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18/12/2009
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Last edited
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04/01/2010
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Date ISRCTN assigned
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04/01/2010
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